Sanséau, Philippe: search on Z-Library

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1

Novelty in the target landscape of the pharmaceutical industry

Agarwal, Pankaj, Sanseau, Philippe, Cardon, Lon R.

Journal:

Nature Reviews Drug Discovery

Year:

2013

Language:

english

File:

PDF, 283 KB

english, 2013

2

Use of genome-wide association studies for drug repositioning

Sanseau, Philippe, Agarwal, Pankaj, Barnes, Michael R, Pastinen, Tomi, Richards, J Brent, Cardon, Lon R, Mooser, Vincent

Journal:

Nature Biotechnology

Year:

2012

Language:

english

File:

PDF, 181 KB

english, 2012

3

Reply to Rational drug repositioning by medical genetics

Sanseau, Philippe, Agarwal, Pankaj, Barnes, Michael R, Pastinen, Tomi, Richards, J Brent, Cardon, Lon R, Mooser, Vincent

Journal:

Nature Biotechnology

Year:

2013

Language:

english

File:

PDF, 109 KB

english, 2013

4

Increased resolution of large DNA fragments by a two dimensional pulse field gel electrophoresis

Philippe Sanséau, Christophe Tiffoche, Abdel-El Kahloun, Olivier Collin, Jean-Paul Rolland, Jean Paul Le Pennec

Journal:

Analytical Biochemistry

Year:

1990

Language:

english

File:

PDF, 3.11 MB

english, 1990

5

Efficiency and specificity of gene isolation by exon amplification

Michael A. North, Philippe Sanseau, Alan J. Buckler, Deanna Church, Amanda Jackson, Ketan Patel, John Trowsdale, Hans Lehrach

Journal:

Mammalian Genome

Year:

1993

Language:

english

File:

PDF, 1023 KB

english, 1993

6

Drug discovery and computational evolutionary analysis

Joanna D. Holbrook, Philippe Sanseau

Journal:

Drug Discovery Today

Year:

2007

Language:

english

File:

PDF, 247 KB

english, 2007

7

The genetics of a pharma merger

Philippe Sanseau, Marie Chabot-Fletcher, Michael J. Browne

Journal:

Drug Discovery Today

Year:

2009

Language:

english

File:

PDF, 235 KB

english, 2009

8

Computational biology approaches for selecting host–pathogen drug targets

James R. Brown, Michal Magid-Slav, Philippe Sanseau, Deepak K. Rajpal

Journal:

Drug Discovery Today

Year:

2011

Language:

english

File:

PDF, 705 KB

english, 2011

9

The role of translational bioinformatics in drug discovery

Natalie S. Buchan, Deepak K. Rajpal, Yue Webster, Carlos Alatorre, Ranga Chandra Gudivada, Chengyi Zheng, Philippe Sanseau, Jacob Koehler

Journal:

Drug Discovery Today

Year:

2011

Language:

english

File:

PDF, 278 KB

english, 2011

10

Electronic health records: Implications for drug discovery

Lixia Yao, Yiye Zhang, Yong Li, Philippe Sanseau, Pankaj Agarwal

Journal:

Drug Discovery Today

Year:

2011

Language:

english

File:

PDF, 342 KB

english, 2011

11

Impact of human genome sequencing for in silico target discovery

Philippe Sanseau

Journal:

Drug Discovery Today

Year:

2001

Language:

english

File:

PDF, 67 KB

english, 2001

12

Transgenic gene knockouts: a functional platform for the industry

Philippe Sanseau

Journal:

Drug Discovery Today

Year:

2001

Language:

english

File:

PDF, 32 KB

english, 2001

13

In silico identification of novel therapeutic targets

D.Malcolm Duckworth, Philippe Sanseau

Journal:

Drug Discovery Today

Year:

2002

Language:

english

File:

PDF, 98 KB

english, 2002

14

A computational view of microRNAs and their targets

James R. Brown, Philippe Sanseau

Journal:

Drug Discovery Today

Year:

2005

Language:

english

File:

PDF, 167 KB

english, 2005

15

Evolutionary relationships of Aurora kinases: Implications for model organism studies and the development of anti-cancer drugs

James R Brown, Kristin K Koretke, Marian L Birkeland, Philippe Sanseau, Denis R Patrick

Journal:

BMC Evolutionary Biology

Year:

2004

Language:

english

File:

PDF, 461 KB

english, 2004

16

The role of positive selection in determining the molecular cause of species differences in disease

Jessica J Vamathevan, Samiul Hasan, Richard D Emes, Heather Amrine-Madsen, Dilip Rajagopalan, Simon D Topp, Vinod Kumar, Michael Word, Mark D Simmons, Steven M Foord, Philippe Sanseau, Ziheng Yang, Jo

Journal:

BMC Evolutionary Biology

Year:

2008

Language:

english

File:

PDF, 964 KB

english, 2008

17

Purification and characterization of a new k-carrageenase from a marine Cytophaga-like bacterium

Philippe POTIN, Alain SANSEAU, Yvan LE GALL, Cyrille ROCHAS, Bernard KLOAREG

Journal:

Year:

1991

Language:

english

File:

PDF, 622 KB

english, 1991

18

Risk in drug trials

Michael R Barnes, Joanna Holbrook, John A Feild, David B Searls, Philippe Sanseau

Journal:

Year:

2007

Language:

english

File:

PDF, 38 KB

english, 2007

19

Cloning of the region between HLA-DMB and LMP2 in the human major histocompatibility complex

Philippe Sanséau, Amanda Jackson, Gabriele Senger, Adrian Kelly, Fiona Francis, Denise Sheer, John Trowsdale

Journal:

Human Immunology

Year:

1994

Language:

english

File:

PDF, 514 KB

english, 1994

20

The micro RNA target paradigm: a fundamental and polymorphic control layer of cellular expression

Barnes, Michael R, Deharo, Steve, Grocock, Russell J, Brown, James R, Sanseau, Philippe

Journal:

Expert Opinion on Biological Therapy

Year:

2007

Language:

english

File:

PDF, 309 KB

english, 2007

21

Integrative clinical transcriptomics analyses for new therapeutic intervention strategies: a psoriasis case study

Qu, Xiaoyan A., Freudenberg, Johannes M., Sanseau, Philippe, Rajpal, Deepak K.

Journal:

Drug Discovery Today

Year:

2014

Language:

english

File:

PDF, 1013 KB

english, 2014

22

A testis-expressed Zn finger gene (ZNF76) in human 6p21.3 centromeric to the MHC is closely linked to the human homolog of the t-complex gene tcp-11

Ragoussis, Jiannis, Senger, Gabriele, Mockridge, Ian, Sanseau, Philippe, Ruddy, Susan, Dudley, Keith, Sheer, Denise, Trowsdale, John

Journal:

Year:

1992

Language:

english

File:

PDF, 4.67 MB

english, 1992

23

Conservation of Synteny between the Genome of the Pufferfish (Fugu rubripes) and the Region on Human Chromosome 14 (14q24.3) Associated with Familial Alzheimer Disease (AD3 Locus)

Michael K. Trower, Suzanne M. Orton, Ian J. Purvis, Philippe Sanseau, John Riley, Chris Christodoulou, Doreen Burt, Chee Gee See, Greg Elgar, Robin Sherrington, Evgeny I. Rogaev, Peter St. George-Hysl

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 260 KB

english, 1996

24

A new dynamic tool to perform assembly of Expressed Sequence Tags (ESTs)

Gill, Robert W., Hodgman, T.Charles, Littler, Chris B., Oxer, Marcus D., Montgomery, Douglas S., Taylor, Steve, Sanseau, Philippe

Journal:

Year:

1997

Language:

english

File:

PDF, 375 KB

english, 1997

25

Released chromatin: linearized DNA for high resolution fluorescence in situ hybridization

Senger, Gabriele, A.Jones, Tania, Fldlerová, Helena, Sanséau, Philippe, Trowsdale, John, Duff, Michael, Sheer, Denise

Journal:

Human Molecular Genetics

Year:

1994

Language:

english

File:

PDF, 4.31 MB

english, 1994

26

Significant obesity‐associated gene expression changes occur in the stomach but not intestines in obese mice

Chen, Jing, Chen, Lihong, Sanseau, Philippe, Freudenberg, Johannes M., Rajpal, Deepak K.

Journal:

Physiological Reports

Year:

2016

Language:

english

File:

PDF, 1.63 MB

english, 2016

27

Systematic prediction of drug combinations based on clinical side-effects

Huang, Hui, Zhang, Ping, Qu, Xiaoyan A., Sanseau, Philippe, Yang, Lun

Journal:

Scientific Reports

Year:

2014

Language:

english

File:

PDF, 875 KB

english, 2014

28

Harnessing public domain data to discover and validate therapeutic targets

Reisdorf, William C., Chhugani, Neha, Sanseau, Philippe, Agarwal, Pankaj

Journal:

Expert Opinion on Drug Discovery

Year:

2017

Language:

english

File:

PDF, 884 KB

english, 2017

29

Systematic Analysis of Drug Targets Confirms Expression in Disease-Relevant Tissues

Kumar, Vinod, Sanseau, Philippe, Simola, Daniel F., Hurle, Mark R., Agarwal, Pankaj

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 766 KB

english, 2016

30

Uncovering novel repositioning opportunities using the Open Targets platform

Khaladkar, Mugdha, Koscielny, Gautier, Hasan, Samiul, Agarwal, Pankaj, Dunham, Ian, Rajpal, Deepak, Sanseau, Philippe

Journal:

Drug Discovery Today

Year:

2017

Language:

english

File:

PDF, 1.44 MB

english, 2017

31

In silico prediction of novel therapeutic targets using gene–disease association data

Ferrero, Enrico, Dunham, Ian, Sanseau, Philippe

Journal:

Journal of Translational Medicine

Year:

2017

Language:

english

File:

PDF, 1.69 MB

english, 2017

32

Uncovering new disease indications for G-protein coupled receptors and their endogenous ligands

Freudenberg, Johannes M, Dunham, Ian, Sanseau, Philippe, Rajpal, Deepak K

Journal:

BMC Bioinformatics

Year:

2018

Language:

english

File:

PDF, 1.75 MB

english, 2018

33

Interleukin-18 as a drug repositioning opportunity for inflammatory bowel disease: A Mendelian randomization study

Mokry, Lauren E., Zhou, Sirui, Guo, Cong, Scott, Robert A., Devey, Luke, Langenberg, Claudia, Wareham, Nick, Waterworth, Dawn, Cardon, Lon, Sanseau, Philippe, Davey Smith, George, Richards, J. Brent

Journal:

Scientific Reports

Year:

2019

Language:

english

File:

PDF, 1009 KB

english, 2019

34

Interleukin-18 as a drug repositioning opportunity for inflammatory bowel disease: A Mendelian randomization study

Mokry, Lauren E., Zhou, Sirui, Guo, Cong, Scott, Robert A., Devey, Luke, Langenberg, Claudia, Wareham, Nick, Waterworth, Dawn, Cardon, Lon, Sanseau, Philippe, Davey Smith, George, Richards, J. Brent

Journal:

Scientific Reports

Year:

2019

File:

PDF, 1009 KB

2019